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Webinar #138
March 17, 2023 (Friday) 12nn
“LABANAN ANG KANSER: Next Generation Sequencing (NGS), Parating Na!”
Presenter:
DR. EUGENE G. ODOÑO I
Medical Specialist III, Department of Laboratories
UP Philippine General Hospital
Reactors:
DR. JANUARIO ANTONIO D. VELOSO
Chair, Department of Laboratories
UP Philippine General Hospital
DR. DENNIS L. SACDALAN
Medical Oncologist Consultant, Department of Medicine
UP Philippine General Hospital
Synthesis & Closing Remarks:
DR. MICHELE SIA H. DIWA
Chief, Division of Molecular Pathology, Department of Laboratories
UP Philippine General Hospital
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March 17, 2023 (Friday) 12nn
Webinar #138
“LABANAN ANG KANSER: Next Generation Sequencing (NGS), Parating Na!”
Over the last 15 years, cutting-edge research has made us better understand cancer as a genetic disease that is borne out of genomic disruptions, which may be a single point mutation, deletion or amplification of segments of chromosomes, and structural rearrangements. These genomic disruptions have driven gene expression changes, activate or silence genes, and thereby alter gene networks and pathways. Globally, efforts to study multiple cancer types continue to be conducted and these are likely to lead to compelling discoveries that may translate to new innovations in diagnostics, prognostication, and therapeutics.
Next generation sequencing (NGS) is an incredible advancement in DNA sequencing wherein we can perform sequencing of a large number of DNA strands simultaneously. This major achievement has allowed us to map the entire human genome in less than 24 hours. What makes NGS different from older, more traditional methods of sequencing is that it does not depend on chain termination. Instead, a corresponding fluorescent signal is emitted and is then detected in real time. NGS has definitely replaced other high-throughput technologies, such as microarrays, for many genomic applications. On a per sample basis, the sensitivity, speed, and reduced cost of performing NGS has made it highly appealing as the platform of choice compared to other sequencing modalities.
In this episode of STOP COVID DEATHS, we take a closer look at innovations in early diagnosis and treatment for cancer involving NGS. Our main speaker is Dr. Eugene G. Odoño I, who is a Medical Specialist III at the UP-PGH Department of Laboratories with reactions coming from Dr. Januario Antonio D. Veloso, who is the Chair of the UP-PGH Department of Laboratories, and Dr. Dennis L. Sacdalan, a medical-oncologist and consultant with the UP-PGH Department of Medicine. The Synthesis and Closing Remarks will be delivered by Dr. Michele Sia H. Diwa, who is the Chief of the Division of Molecular Pathology of the UP-PGH Department of Laboratories.
Join your credible online community in understanding how NGS can help cancer patients. Together, we can STOP C.O.V.I.D. DEATHS!